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One of the most common questions we get is “How do I turn on Out of office replies” so I can go on holiday”
This is a user setting directly in Outlook and you can easily do it on your computer.
There are two ways to send automatic out-of-office replies in classic Outlook.
Select File on the left end of the ribbon:

If you have the Automatic Replies button, continue following the steps below.
If you don’t have the Automatic Replies button, then go to use rules to send an out of office message and follow the steps.


Turn off automatic out-of-office replies
When classic Outlook is setup to send automatic replies, you’ll have a message under the ribbon with this information. Select Turn off to disable automatic out-of-office replies. If you want to modify the dates for your automatic reply or the message sent, use the steps above to modify your settings.

Thanks to Microsoft for this excellent article